Built at the Internet Archive
Sites for this collection are listed below. Narrow your results at left, or enter a search query below to find a site, specific URL or to search the text of archived webpages.
Page 1 of 3 (259 Total Results)Next Page ►
Sort By:
Description: Cell therapy has shown promising results for treating and curing a large range of diseases, from cancer to diabetes. The principles of cell therapy are easy to describe: cells (possibly modified) are injected into patients. Cell therapy is now a reality in Europe: in August 2018 the first two treatments for patients with blood cancer were approved; more of them are about to successfully conclude the approval path. What hinders the large-scale uptake of cell therapy is its costs: culturing enough cells of high quality requires specialised personnel and infrastructure, which only a few centres can afford. The market asks for a scalable cell culture platform that can produce large quantities of high quality cells at much lower costs than done nowadays. To address this need, we have developed the Facer – the first fully-autonomous cell culture platform. The Facer can manufacture billions of high-quality cells starting from the small quantity (about 500,000 cells) of a tissue biopsy without the need of human intervention, thanks to a unique patented iterative process. Our product is at TRL 7; its performances, in terms of quality and costs, are superior to any competitor commercially available. We have developed the Facer over the course of 5 years thanks to cash investments of over €3 million. In the Phase 2 project we will finalise the product, perform a validation with external partners, gain the CE marking (our product is not a medical device), and find a distributor and a launching customer. We will initially tackle the European market to then expand globally once that the local regulatory barriers are overcome. In 2024, after 5 years from the first sale, our turnover will surpass the €60 million and our EBITDA will be over €36 million. Our innovation can enable affordable cell therapies at a large scale and change the life of millions of patients who suffer from diseases that have been deemed 'incurable' so far.
Loading Wayback Capture Info...
Loading video data...
Description: This research project focuses on several key Direct Energy Deposition (DED) Additive Manufacturing (AM) processes that have great potential to be used as cost-effective and efficient repairing and re-manufacturing processes for aerospace components such as turbine blades and landing gears. This project aims to conduct fundamental research to understand the material integrity through chosen DED AM processes, the accuracy and limitations of these deposition processes, effective defect geometry mapping and generation methods, and automated and hybrid DED and post-deposition machining strategies. This project intends to connect repair and re-manufacturing strategies with design through accurate DED process simulation and novel multi-disciplinary design optimisation (MDO) methods to ultimately reduce the weakness of aerospace component at design stage and prolong their the lifecycles. Both powder-based and wire-based DED systems will be investigated to establish an across-the-board comparative study. The data collected through this comprehensive comparative study will be extremely valuable for the OEMs of this project (i.e. GKN, PWC, and HDI) to understand the pros and cons of these DED systems and will help them to select suitable repair and re-manufacturing strategies. The tests conducted in this research are also extremely beneficial for the SMEs in this project (i.e. Liburdi, AV&R, DPS) to validate their existing repairing systems and techniques.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF SHEFFIELD
Country: United Kingdom
Description: Wind energy is one of the fastest growing sectors in the world's energy markets. According to the EWEA, the European wind market it is expected to grow consistently at a compound annual growth rate of 9.8%. As annual blade failures are estimated at around 3,800 with poor maintenance the most common cause of accidents, ensuring the integrity of blades is a key issue with respect to the business, safety and the environment. The overall problem envisaged is the lack of effective condition monitoring systems for the blades, representing a business opportunity for the project’s partners Hence, the Project aims to commercialize a novel solution, BladeSave, marketed as a fusion between a Fibre Optic Structural Health Monitoring System providing multi-sensing capability and a management software incorporating risk based inspection data analysis and offering a comprehensive solution for blade monitoring, repair and management. Based on existing technologies developed by the partners at TRL6, BladeSave will assist WFOs in satisfying newly imposed regulations by the European Agency for Safety and Health at Work (amendments to EN 50308) and benefit European ISPs in the CM services market, giving them a competitive edge over global rivals. Our product market target consists predominantly of the WTFs installed before 2011 (currently around 71,620 in Europe) as old wind turbines have an average annual maintenance cost larger than newer models, are not covered by warranties and offer a bigger risk of catastrophic failures. The project brings together five experienced companies with a unique set of skills and expertise in the wind industry. BladeSave will have an impact on both European and foreign markets, and over the five year sales projection, we forecast a total cumulative gross profits of at least €48 million, a return of EU investment of 23:1 and the creation of about 380 jobs within consortium and associated companies which are part of the supply chain.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: RENEWABLE ADVICE LTD
Country: United Kingdom
Description: Dengue virus (DENV) is the most prevalent arthropod-borne viral pathogen and infects about 400 million people worldwide
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: CARDIFF UNIVERSITY
Country: United Kingdom
Description: Environmental factors, including the heavy metal mercury, are recognized as having a dominant influence on the aetiology and prevalence of neurodevelopmental behavioural disorders. This proposal will develop a new model for assessing the role of gene:environment interactions, specifically genetic predisposition for toxicity, in risk for disease, and identify early markers predictive of toxicity and later phenotypes. This will directly relate to the EC work program for Health, demographic change and wellbeing, with respect to both 'Personalized medicine' for non-communicable diseases and 'Early development' addressing mental health from childhood to older ages. The project uses the zebrafish model to investigate the relationship between glutathione-S-transferase (GST)-related genetic background, developmental exposure to mercury, and risk for neurodevelopmental disorders. This will be achieved by exposure of wild-type and CRISPR-generated Gst mutant embryos to mercury, and testing whether genetic predisposition leads to increased risk for toxin-induced behavioural phenotypes. We will test for altered biochemical, transcriptomic and epigenomic modifications that may serve as potential early markers for insult. The results obtained in this proposal will have significant impact on the ability to conduct individual and population specific toxicity risk assessment, and may lead to novel measures for early detection of increased risk and alleviation of potential adverse outcomes. The high-quality original research presented in the proposal will not only enable the Experienced Researcher to reach a position of professional maturity in her career, but will also allow her to develop a spectrum of new and interdisciplinary skills, integrating her previous training and knowledge into the behavioural genetics skills set. This project will also allow Dr. Brennan's group to integrate developmental toxicology into existing behavioural research, and will generate new collaborations.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: QUEEN MARY UNIVERSITY OF LONDON
Country: United Kingdom
Description: The aim of the fellowship is to pioneer a synthetic method to form carbon–carbon bonds from the coupling of two carbon–fluorine bonds. This method will result in new routes to fluorinated biaryls, organic molecules that are used in materials science or as the active ingredient in pharmaceuticals and agrochemicals. It will open up new pathways to using inexpensive and environmentally persistent fluorocarbons in synthesis.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Country: United Kingdom
Description: This project aims to help people with dementia engage in social contexts to improve psychosocial wellbeing. People who are affected by Alzheimer’s disease or other dementias often face cognitive, behavioural and psychosocial difficulties, including impairment and degeneration of memory and of perceptions of identity. In a social context, this can cause difficulties of recognizing, relating to and empathising with other people. These difficulties often pose a challenge for engaging socially, reinforcing their effects and reducing personal well-being.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF WOLVERHAMPTON
Country: United Kingdom
Description: This grant will develop and translate a unifying framework for optimal decision-theory, and observations of natural systems, to design distributed algorithms for decentralised decision-making. This will enable a technological step-change in techniques for controlling distributed systems, primarily demonstrated during the grant by decentralised control of robot swarms. These algorithms and associated methodology will also provide hypotheses and tools to change the way scientists think about and interrogate natural decision mechanisms, from intracellular regulatory networks, via neural decision circuits, to decision-making populations of animals. Specific objectives are:
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF SHEFFIELD
Country: United Kingdom
Description: The ENCOMPASS project principally aims to create a fully digital integrated design decision support (IDDS) system to cover the whole manufacturing chain for a laser powder bed fusion (L-PBF) process encompassing all individual processes within in. The ENCOMPASS concept takes a comprehensive view of the L-PBF process chain through synergising and optimising the key stages. The integration at digital level enables numerous synergies between the steps in the process chain and in addition, the steps themselves are being optimised to improve the capability and efficiency of the overall manufacturing chain.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE MANUFACTURING TECHNOLOGY CENTRE LIMITED
Country: United Kingdom
Description: There is a need to develop an autonomous, reliable, cost effective technology to map vast terrains, in terms of mineral and raw material contents which will aid in reducing the cost of mineral exploration, currently performed by ROVs and dedicated SSVs and crew. Furthermore there is a need to identify, in an efficient and non-intrusive manner (minimum impact to the environment), the most rich mineral sites. This technology will aid the seabed mining industry, reduce the cost of exploration and especially the detailed identification of the raw materials contained in a mining sites and enable targeted mining only of the richest resources existing.
Loading Wayback Capture Info...
Loading video data...
Description: EuroPOND will develop a data-driven statistical and computational modeling framework for neurological disease progression. This will enable major advances in differential and personalized diagnosis, prognosis, monitoring, and treatment and care decisions, positioning Europe as world leaders in one of the biggest societal challenges of 21st century healthcare. The inherent complexity of neurological disease, the overlap of symptoms and pathologies, and the high comorbidity rate suggests a systems medicine approach, which matches the specific challenge of this call. We take a uniquely holistic approach that, in the spirit of systems medicine, integrates a variety of clinical and biomedical research data including risk factors, biomarkers, and interactions. Our consortium has a multidisciplinary balance of essential expertise in mathematical/statistical/computational modelling; clinical, biomedical and epidemiological expertise; and access to a diverse range of datasets for sporadic and well-phenotyped disease types.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY COLLEGE LONDON
Country: United Kingdom
Description: Cell surface carbohydrates play key roles in cell recognition mechanisms. O-glycosylation is a ubiquitous post-translational modification that is highly dynamic and responsive to cellular stimuli through the action of cycling enzymes. Expression of specific O-glycans is linked to changes in gene expression in, for example, inflammatory bowel disease, cystic fibrosis and several types of cancer.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF BRISTOL
Country: United Kingdom
Description: Insight into dynamic processes such as uptake and intracellular trafficking and signalling of small molecules and proteins in cells is key in basic biology and drug development. The use of bioorthogonal chemical reactions for labelling and probing specific biomolecules is an exciting option but a very challenging task as these transformations should proceed very rapidly in physiological conditions with complete chemoselectivity. So, in this application we propose to achieve site-selective protein labelling by the introduction of a non-canonical Cys-cyclobutene aminoacid and a very fast alkene chemoselective ligation reaction. The small size of the proposed alkene-tagged aminoacid should not interfere with the protein structure, function, activity or localisation in contrast with other fluorescent tags such as the use of fusion proteins as GFP. This project aims at 1) developing a new photo triggered [2\2] cycloaddition bioorthogonal ligation between two alkene containing partners and to apply the already established IEDDA reaction between tetrazines and dienophiles. While the use of light as a trigger offers the possibility for an improved spatial and temporal resolution, the use of tetrazine fluorogenic probes allows for ‘turn-on’ fluorescence on their rapid reaction with dienophiles 2) use these optimized reaction to study apoptosis in cells and tissues by introducing the proposed Cys-cyclobutene non-canonical amino acid into C2A Domain of Synaptotagmin-I followed by the ligation reaction ex vivo and in vivo
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
Country: United Kingdom
Description: In EU and Australia, every year thousands of square miles of forests and other lands burn due to wildfires. These fires cause important economic and ecological losses, and often, human casualties. Both EU and Australian governments are aware of how crucial it is to improve wildfires’ management and containment . Scientists from different specialties, both in EU and Australia, have already developed methods and models in order to improve the management and decision process pertaining to preparedness and response phases in case of bushfire. The present project, named Geospatial based Environment for Optimisation Systems Addressing Fire Emergencies (GEO SAFE), aims at creating a network enabling the two regions to exchange knowledge, ideas and experience , thus boosting the progress of wildfires knowledge and the related development of innovative methods for dealing efficiently with such fires.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF GREENWICH
Country: United Kingdom
Description: The Green INSTRUCT project will develop a prefabricated modular structural building block that is superior to conventional precast reinforced concrete panels by virtue of its reduced weight, improved acoustic and thermal performance and multiple functionalities. The Green INSTRUCT block consists of over 70% of CDW in weight.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: BRUNEL UNIVERSITY LONDON
Country: United Kingdom
Description: Bone density loss is a natural process that affects us all as we age. As the loss advances, so does the risk of fracture. The lack of warning symptoms or routine tests results in a late detection of severe density loss (osteoporosis), often when the first fracture occurs. Besides being a major social burden, in the EU it entails costs of €37 bn/year in treatment, disability or productivity loss, which could be alleviated if population-wide bone health screening methods were available. Today, measurement of bone mineral density (BMD) is only available through scarce and expensive DEXA scans, limiting testing to referred individuals grouped as high risk of osteoporosis. In response, we at IBEX Innovations have developed and patented IBEX-Quantitative Digital Radiography (IBEX-QDR). Conceived as a cost-efficient upgrade for standard digital radiography systems, it enhances the quality of digital X-ray images and enables these systems to measure BMD. All while reducing by 2-fold the X-ray dose needed to obtain the image. Altogether, IBEX QDR will unleash the diagnostic potential of digital radiology, enabling routine screening of bone density with any standard X-ray examination. In a Phase 1 project we confirmed the market opportunities for IBEX-QDR, outlined technical optimisations and achieved high-level engagement with X-ray detector and system manufacturers and healthcare providers. Now in Phase 2 we aim to reach market readiness by finalising the technological development, completing its clinical validation and securing the business aspects of the project. Once in the market, IBEX QDR will bring significant benefits for healthcare systems (early diagnosis and lower impact of ageing diseases), professionals (safer and simplified work-flows) and public health (lower radiation dose and less X-ray induced cancer). In turn, in 5 years it will provide us €16.7 million profits, 16 new people and a ROI of €9.37 per euro invested, representing c.1% of the target market.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: IBEX INNOVATIONS LTD
Country: United Kingdom
Description: The Future Media Internet (FMI) will be driven by evolving existing over-the-top (OTT) solutions towards a stronger integration with emerging programmable communication and computing infrastructures to address consumer demand for personalised, interactive, mobile and localised media experiences. Creating a trusted platform that brings together technology, creative sectors and consumers in the development of pioneering media applications and services will be crucial to drive European innovation and competitiveness. FLAME will address this goal by establishing an FMI ecosystem based on the largescale experimentation of novel FMI products and services using real-life adaptive experimental infrastructures encompassing not only the compute and storage facilities but also the underlying software-enabled communication infrastructure. FLAME’s ecosystem will engage both the creative industries (broadcast, gaming, etc.) and ICT industries (telcos, services) responsible for online distribution, broadcast, communication, and distribution of digital content. Through acceleration methodologies and an advanced experimentation platform (surrogate service management, adaptive service routing, experimental media service chains and experimentation toolbox), FLAME will allow industry, SMEs and entrepreneurs to conduct experiments in real-life experimental infrastructures and gain insight into the performance, acceptance and viability of solutions. FLAME’s innovation potential will be maximised by establishing FLAME Trailblazers (Bristol, Barcelona) to show the way for FLAME Replicators across Europe using a replication process based on best practice sustainability, governance, and engagement models, and infrastructure standards and specifications. A 3rd party investment strategy will create a vibrant FMI ecosystem that adds significant value to current FIRE\ efforts, and puts in place measures for long term sustainability.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF SOUTHAMPTON
Country: United Kingdom
Description: Families in Western countries have received a great deal of attention from social scientists but there is less information on family life in other regions of the world. Given its growing rapidly in global influence, China represents a crucial region for sociological advancement and understanding. There have been profound changes in the Chinese family over the last century as a result of industrialization, urbanization, the influence of the West and the political interventions carried out by the Communist Party since 1949. Existing scholarship has shown how the structure and function of Chinese families have adapted to changing political and economic circumstances but little is known about the changes in intimate spheres of Chinese families. This project will approach the subject of modern Chinese family life from an unconventional angle, analysing it as a process of practices and experiences. By setting a new agenda that moves from structures of family relationships to the quality of relationships and through examining ‘doing intimacy’, this project will take a closer, fresher, critical look at the Chinese family dynamics as they are lived. Informed by the emerging literature on gender, intimacy and modernity, this project will examine intergenerational relations as well as gender and sexual relations in the family. Is there an intimate revolution taking place? How is ‘modernity’/’tradition’ closely linked with practices of intimacy? To what extent can doing intimacy be a site of empowerment/domination for women? What will the study of Chinese families tell us about agency and local/global change? Through a multi-sited ethnography (mainland China, Hong Kong and Taiwan), this study will also compare practices of intimacy in various sites and examine whether/how they are by-products of particular socio-cultural configurations. It will identify the extent to which changes in Chinese families mirror changes in the West and the factors that contribute to these changes.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: SCHOOL OF ORIENTAL AND AFRICAN STUDIES ROYAL CHARTER
Country: United Kingdom
Description: Motor learning (the ability of the brain to learn and update how an action is executed) is a fundamental process which influences many aspects of our lives such as learning to walk during childhood; the day-to-day behavioural adjustments required as an adult or in healthy ageing; and the rehabilitation process following an illness or injury. Despite the impact to society, it has proved extremely difficult to develop interventions that significantly enhance human motor learning. Therefore, devising protocols which optimise motor learning is a state-of-the-art research question that promises to deliver scientific, clinical and societal impact.Seeking reward and avoiding punishment are powerful factors in motivating humans to alter behaviour during cognition-based learning (selecting which action to perform), with sensitivity to reward and punishment being biased by the availability of dopamine in the brain. Intriguingly, reward and punishment are also known to affect generic motor learning (deciding how an action is executed) tasks which involve multiple underlying mechanisms. However to establish their potential for optimizing motor learning, we must understand how explicit reward- and punishment-based motivational feedback impact motor learning systems with unique computational and anatomical features (use-dependent/model-free/model-based). Using an unprecedented combination of behavioural analysis, computational modelling, genetics and pharmacology, MotMotLearn will provide the first systems-based account of how reward, punishment and dopamine influence motor learning. This novel approach will enable MotMotLearn to develop theoretically-grounded protocols that utilise reward/punishment in conjunction with dopaminergic medication to optimise motor learning in healthy individuals and stroke patients suffering motor impairments. MotMotLearn will have a profound scientific impact in motor learning with applications to development, ageing, rehabilitation and sports.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF BIRMINGHAM
Country: United Kingdom
Description: Programming languages with probabilistic features are used extensively in computer science and beyond, to model uncertainty, perform quantitative analysis, inference and much more. To analyse programs in such languages, it is essential to have effective tools and techniques for approximate reasoning: for instance, determining the chance of congestion in a network, or the chance of failure of a system component. CARBS proposes a general mathematical framework of compositional proof techniques for approximate reasoning, with two essential points of focus: general applicability, to deal with the wide variety of different quantitative languages and models, and compositionality, to deal with large-scale systems. A motivating case study and application for the developed proof techniques is ProbNetKAT, a probabilistic language for describing randomized protocols and analysing quantitative properties in networks such as throughput or chance of failure. Approximate reasoning about such network programs is an important but also challenging problem, and the abundance of possible case studies will allow to immediately evaluate and apply the developed proof techniques. Approximate reasoning requires to move from behavioural equivalence to behavioural metrics, formalising how far apart two programs are. CARBS is based on integrating behavioural metrics in bialgebraic semantics, a categorical approach for a systematic study of languages and calculi based on the combination of algebra and coalgebra. Coalgebra allows to define behavioural metrics, in a general manner, whereas algebra integrates compositionality in the associated proof techniques. The overall envisaged result of CARBS is an extension of bialgebraic semantics to quantitative systems, providing on the one hand fundamental insights about quantiative coalgebras and compositionality, and on the other hand concrete, effective proof techniques for approximate reasoning.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY COLLEGE LONDON
Country: United Kingdom
Description: I propose to study phases of matter that emerge in quantum systems far away from equilibrium. This is a very challenging and urgent problem as the recent experimental advances in cold atoms, trapped ions and solid-state physics in general, put us in front of possibilities that we never had in the past. The degree of control that we have nowadays on single atoms, the temperatures we are able to reach and the capability to keep an exact quantum evolution for long times, are only some of the several advances with the potential to disclose new physical phenomena with huge impact on society in the next years. Experiments and industry are moving fast towards building new devices, but most of the theoretical understanding still needs to be developed.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Country: United Kingdom
Description: MAGIC Post Stroke Project Team has united members from across Europe, dedicated to enable significant change in the delivery of health & social care (H&SC) services for patients post stroke. The consortium has recognised a significant gap in care associated with the recovery of such patients & we need a new way of meeting the needs of 508,000 new post stroke EU citizens/ year. Demographic changes are such that H&SC systems are failing to keep pace with demand & are not fit for purpose. By working in new ways & by reengineering systems with novel innovative technology & solutions we can think differently about our approach to care & improve the well-being for our patients; optimising the opportunity for recovery post stroke. Presently 1/3rd of all stroke patients are discharged from hospital with a significant change to life style, well-being, health status & independence. Community H&SC services do not enable patients to make a sufficient recovery post stroke. A search of state of the art technologies indicated much progress in the development of technologies to assist patients but no system is available to significantly affect rehabilitative improvement to scale; with no solution integration with H&SC services. Therefore, Public Procurers cannot go to open tender to deploy effective technology to solve system failures. The MAGIC Consortium recognised Pre-Commercial Procurement (PCP) as the only way to stimulate the market to find a solution to our common problem. MAGIC is an essential & strategically critical programme for the Team to optimise a patient’s recovery, to modernise H&SC systems to meet demand & to stimulate research, development & innovation. MAGIC will also stimulate European industry to become a global leader in this innovative field. Use of PCP is of particular interest to the consortium members & is new for many. Therefore, observer states will participate to contribute to the Pan-European improvement in care and to proactively share PCP knowledge.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: REGIONAL BUSINESS SERVICES ORGANISATION
Country: United Kingdom
Description: One of the most profound and long-lasting effects of the war efforts of all major combatant nations during the First World War was the high number of casualties caused by modern industrial warfare. Examining the case of Britain, this project asks what formal and informal structures developed in the interwar years to provide medical and social care to the unprecedented number of war disabled. It further explores how these different forms of care both were shaped by gendered understandings of care-giving and utilized gender to mobilize public and private support for disabled ex-servicemen. While there have been a number of studies of charitable organizations established for the care of disabled ex-servicemen, and of the relationships between the State, the soldier and his family in this era, this is the first study to examine the role of these formal institutions alongside and in relation to the informal social and medical care provided by the family in this period. Through its examination of issues of social, political and domestic responsibility for the care of disabled ex-servicemen, issues which continue to have relevance in light of the survival of service personnel from conflicts such as Iraq and Afghanistan who have suffered massive injuries and multiple amputations, the project seeks not only to engage with historical discussions of the development of medical practice in the first half of the twentieth century but also, through engagement with current policy makers working with and for disabled service personnel, to make a significant intervention into contemporary social policy relating to the provision of medical and social care. By utilizing the methodological prism of gender studies, this project also explores the ways in which medical and social care were gendered to interrogate social and cultural understandings of care-giving in the first half of the 20th century and thereby gain greater insight into the relationships between men, women and care.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF LEEDS
Country: United Kingdom
Description: 'The proposed ITN entitled 'Modelling and computation of Shocks and Interfaces'
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF SUSSEX
Country: United Kingdom
Description: Regulators and industries are challenged by the difficulty to analyse and predict the impact of nonlinear environmental processes on short-term and long-term responses of ecosystems to environmental change. Until very recently, the development of most conventional monitoring, forecasting and prediction tools has been based on the assumption of stationary environmental systems. In the context of global change these tools are increasingly pushed towards and even beyond their design limits (the latter resulting in the first line from the prevailing limitations in spatial and temporal resolution of environmental observations).
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF BIRMINGHAM
Country: United Kingdom
Description: “World literature is literature that circulates globally. It is mostly in English. Its main genre is the novel.” These are caricatures of how World literature as a set of discourses is shaping the field of literary studies, but in fact Non-Western literatures are positioned with reference to a single global timeline and a single map, and translations supposedly ensure that worthy texts enter the global canon. What does not circulate globally is provincial, not good enough, not “world literature”.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: SCHOOL OF ORIENTAL AND AFRICAN STUDIES ROYAL CHARTER
Country: United Kingdom
Description: 'In MuMMER ('MultiModal Mall Entertainment Robot'), we propose to address the important and growing market of consumer entertainment robotics by advancing the technologies needed to support this area of robotics, and also by explicitly addressing issues of consumer acceptance, thus creating new European business and employment opportunities in consumer robotics. Specifically, we will develop a humanoid robot (based on Aldebaran's Pepper platform) able to engage and interact autonomously and naturally in the dynamic environments of a public shopping mall, providing an engaging and entertaining experience to the general public. Using co-design methods, we will work together with stakeholders including customers, retailers, and business managers, to develop truly engaging robot behaviours, including telling jokes or playing games, as well as providing guidance, information, and collecting customer feedback. Crucially, our robot will exhibit behaviour that is socially appropriate, combining speech-based interaction with non-verbal communication and human-aware navigation. To support this behaviour, we will develop and integrate new methods from audiovisual scene processing, social-signal processing, high-level action selection, and human-aware robot navigation.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF GLASGOW
Country: United Kingdom
Description: Translocation of ions and molecules is ubiquitous in biology and technology. Despite the tremendous amount of technical development, biological systems are still much more sophisticated in exerting exquisite control over active and passive translocation through nanopores in membranes than their existing synthetic mimics. This proposal aims to build novel designer nanopores that can match naturally evolved systems. For this we have to control all three stages of translocation: 1) diffusion and entry into, 2) diffusion in, and 3) exit from the nanopore. To gain fundamental insight into the translocation process we will employ microfluidic channels combined with holographic optical tweezers. Results from the microscale model system will be directly translated to nanoscale pores built with DNA origami nanotechnology. Our microfluidic experiments will automatically track diffusing spherical and non-spherical particles in artificial channels. Facilitated membrane transport will be mimicked by holographic optical tweezers providing full control over the translocation process. We will clarify how translocation depends on particle-particle, particle-channel, and particle-channel-entrance interactions.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
Country: United Kingdom
Description: Spirit possession cults puzzle Western observers, particularly when they appear in supposedly secular urban environments. Muslim migrants from North Africa, seeking to establish new lives in Southern Europe, have to negotiate the continuity of such ritual practices with the constraints and expectations imposed on them by their new social contexts. But the legitimacy of these cults is contested also in their homeland, where they face increasing pressures by religious fundamentalism. Space and its organization, especially in urban settings, play an important part in these disputes. In Morocco, spirits are thought to reside in particular places, such as tombs, sanctuaries, or street corners. How do possession cults continue to be practiced when spirits’ spaces of residence have to be abandoned or undergo demolition? This research compares the continuities and ruptures in cult performances as the spaces that host them are affected by both forced displacement and voluntary diasporic migration. I will observe the resettlement of a slum in Casablanca, and compare it with two Southern European neighborhoods where Moroccan practitioners of spirit cults struggle to maintain their specific version of Islam in multicultural, post-colonial and post-secular urban settings, exposed to disruptive processes such as gentrification. By applying an ethnographic methodology to comparative urbanism, I aim to shed light on how different spatial transformations affect ritual performances that are meant to protect communities from social disintegration. I argue that different urban policies on both sides of the Mediterranean mutually reinforce, resulting in an overall transformation of cultural practices in transnational communities. Examining how migrants adapt localized ritual practices such as spirit possession cults to increasingly transient urban settings, furthers our understanding of the spatial and cultural dimensions that enable or prevent integration.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF LEICESTER
Country: United Kingdom
Description: My proposal consists of two strands linked by a common theme--namely a concern for the impact of disasters, in financial markets and more generally--and by a shared methodology.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE
Country: United Kingdom
Description: There is increasing evidence that intense commercial fishing pressure is not only depleting fish
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF GLASGOW
Country: United Kingdom
Description: 'Modern astrophysics has pushed the observational frontier to a time a billion years after the Big Bang. Lying beyond this frontier is the period when the first stars and galaxies formed, whose light heated and ionized the Universe in the process known as reionization. Understanding this 'epoch of reionization' would fill in a key missing period in our picture of the history of the Universe. Existing observational techniques have scratched the surface, but new observational techniques are required to truly understand this early period of galaxy formation. My work will lay the theoretical foundations for three novel probes of this period - 21 cm tomography, the 21 cm global signal, and line intensity mapping - that would enable three dimensional maps of the epoch of reionization. If realized through challenging radio-frequency observations, these techniques would transform our understanding of the first galaxies.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Country: United Kingdom
Description: The proposed research programme addresses issues of fundamental and technological importance in quantum information science and its interplay with complexity. The main aim of this project is to provide a new paradigmatic foundation for the characterisation of quantumness in cooperative phenomena and to develop novel platforms for its practical utilisation in quantum technology applications.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF NOTTINGHAM
Country: United Kingdom
Description: Radio signals are core to space systems and services; they are the backbone of satellite broadcasting & communications and further represent the primary underpinning technology of the nearly ubiquitous space-based radio navigation services as well as a large number of Earth observation instruments. Radio technologies are therefore central in defining the investment return for a wide range of missions and reflect to a significant fraction of the combined space and ground segment infrastructure. As the frightening rates of concurrent advances in space-related services, business models and technologies are driving the space ecosystem to a new age, the need to re-invent radio technologies for space is becoming increasingly urgent; while the sector is proactively looking for the next game changer, a whole new class of emerging and forecasted missions place urgent demands for drastic reduction in cost with a concurrent radical improvement in throughput, agility, volume/mass and power consumption.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: HERIOT-WATT UNIVERSITY
Country: United Kingdom
Description: The introduction and global roll out of eMBB service within 5G raises coverage and network dimensioning issues in underserved and unserved areas, especially in low ARPU regions of emerging markets, and on mobile platforms (e.g. vessels and aircraft). Satcom systems are the only economic solution to address these scenarios provided that they are seamlessly integrated into the future 5G architecture and optimum efficiency is achieved via technological synergies between 5G mobile and satcom systems.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: AVANTI COMMUNICATIONS LTD
Country: United Kingdom
Description: Science4CleanEnergy, S4CE, is a multi-disciplinary consortium, of world-leading academics, research laboratories, SMEs and industries. S4CE will develop a project that includes fundamental studies of fluid transport and reactivity, development of new instruments and methods for the detection and quantification of emissions, micro-seismic events etc., lab and field testing of such new technologies, and the deployment of the successful detection and quantification technologies in sub-surface sites for continuous monitoring of the risks identified by the European Commission. S4CE leverages approximately 500M EUR in existing investments on 4 scientific field sites. S4CE will utilize monitoring data acquired during the project in these field sites on which (a) it will be possible to quantify the environmental impact of sub-surface geo-energy applications; (b) new technologies will be demonstrated; (c) data will be collected during the duration of the project, and potentially after the end of the project. Using reliable data, innovative analytical models and software, S4CE will quantify the likelihood of environmental risks ranging from fugitive emissions, water contamination, induced micro-seismicity, and local impacts. Such quantifications will have enormous positive societal consequences, because environmental risks will be prevented and mitigated. S4CE set up a probabilistic methodology to assess and mitigate both the short and the long term environmental risks connected to the exploration and exploitation of sub-surface geo-energy. S4CE will maintain a transparent dialogue with all stakeholders, including the public at large, the next generation of scientists, academics and industrial operators, including training of young post-graduate students and post-doctoral researchers. S4CE will deliver the independent assessment of the environmental footprint related to geo-energy sub-surface operations, having as primary impact the assistance to to policy making.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY COLLEGE LONDON
Country: United Kingdom
Description: Robot-assisted minimally invasive surgery (RAMIS) offers many advantages when compared to traditional MIS, including improved vision, precision and dexterity. While the popularity of RAMIS is steadily increasing, the potential for improving patient outcomes and penetrating into many procedures is not fully realised, largely because of serious limitations in the current instrumentation, control and feedback to the surgeon. Specifically, restricted access, lack of force feedback, and use of rigid tools in confined spaces filled with organs pose challenges to full adoption. We aim to develop novel technology to overcome barriers to expansion of RAMIS to more procedures, focusing on real-world surgical scenarios of urology, vascular surgery, and soft tissue orthopaedic surgery. A team of highly experienced clinical, academic, and industrial partners will collaborate to develop: i) dexterous anthropomorphic instruments with minimal cognitive demand ii) a range of bespoke end-effectors with embedded surgical tools using additive manufacturing methods for rapid prototyping and testing utilizing a user-centred approach, iii) wearable multi-sensory master for tele-operation to optimise perception and action and iv) wearable smart glasses for augmented reality guidance of the surgeon based on real-time 3D reconstruction of the surgical field, utilising dynamic active constraints and restricting the instruments to safe regions. The demonstration platform will be based on commercial robotic manipulators enhanced with the SMARTsurg advanced hardware and software features. Testing will be performed on laboratory phantoms with surgeons to bring the technology closer to exploitation and to validate acceptance by clinicians. The study will benefit patients, surgeons and health providers, by promoting safety and ergonomics as well as reducing costs. Furthermore, there is a potential to improve complex remote handling procedures in other domains beyond RAMIS.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL
Country: United Kingdom
Description: From Lebanese immigrants in Argentina to Iraqi refugees in Sweden, Eastern Christians can be found today scattered across the entire world. Too often, however, this global migration has been seen purely as a modern development, one arising from contemporary political and confessional events in the Middle East, while in fact this phenomenon had its roots in the early modern period. From the sixteenth century onwards, Christians from the Ottoman Empire set out for distant worlds and foreign lands, travelling as far as Europe, India, Russia, and even the Americas and leaving traces of themselves across countless European and Middle Eastern archives, chanceries, and libraries. This transnational, ground-breaking project will gather all of these disparate sources into a single analytical frame to uncover, for the first time, the global and connected histories of Eastern Christianity in the early modern world. Through the work of a team of researchers under the close supervision of the PI, the project will reconstitute and analyse a ‘lost archive’ of literary, documentary, and printed sources in three continents, ten languages, and dozens of archives. Under the expert leadership of the PI, the project will include a robust strategy for dissemination, which will successfully bridge the fields of Middle Eastern, European, and global history. In doing so, this project will respond directly to one of the most pressing conceptual challenges facing global history today, that is, how to link the study of the micro-scale level of everyday life to the macro-narratives emphasised by global historians. Underlying this project, therefore, is a major intervention that seeks to advance a rigorous form of global history, and one which preserves philology and source criticism at the heart of its methodology. The outcomes of the project will include print-publications, workshops, and a searchable database of all writings by Eastern Christians from 1500 to 1750.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Country: United Kingdom
Description: Aquaculture is one of five sectors in the EU's Blue Growth Strategy, aimed at harnessing untapped potential for food production and jobs whilst focusing on environmental sustainability. TAPAS addresses this challenge by supporting member states to establish a coherent and efficient regulatory framework aimed at sustainable growth. TAPAS will use a requirements analysis to evaluate existing regulatory and licensing frameworks across the EU, taking account of the range of production environments and specificities and emerging approaches such as offshore technologies, integrated multi-trophic aquaculture, and integration with other sectors. We will propose new, flexible approaches to open methods of coordination, working to unified, common standards. TAPAS will also evaluate existing tools for economic assessment of aquaculture sustainability affecting sectoral growth. TAPAS will critically evaluate the capabilities and verification level of existing ecosystem planning tools and will develop new approaches for evaluation of carrying capacities, environmental impact and future risk. TAPAS will improve existing and develop new models for far- and near-field environmental assessment providing better monitoring, observation, forecasting and early warning technologies. The innovative methodologies and components emerging from TAPAS will be integrated in an Aquaculture Sustainability Toolbox complemented by a decision support system to support the development and implementation of coastal and marine spatial planning enabling less costly, more transparent and more efficient licensing. TAPAS partners will collaborate with key industry regulators and certifiers through case studies to ensure the acceptability and utility of project approach and outcomes. Training, dissemination and outreach activities will specifically target improvement of the image of European aquaculture and uptake of outputs by regulators, while promoting an integrated sustainable strategy for development.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF STIRLING
Country: United Kingdom
Description: This proposal was developed in the context of the medical need to tackle the clinical consequences of obesity-related diseases more holistically. Dysregulation of common molecular pathways that govern the physiological functioning of adipocytes, immune cells and prostate epithelium cells have been reported in immuno-metabolic disease (such as obesity) and several cancers. The individual projects described in the proposal will investigate regulators of these pathways with a focus on a recently described family of pseudokinases, namely tribbles proteins, which have a key role in controlling immunity, metabolism and cancer, and which here will serve as prototypical examples for integrative metabolocentric cancer research. Tribbles are envisaged to contribute directly to the development and progression of prostate cancer, the prognosis of which is substantially worsened in individuals with immuno-metabolic disease.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF SHEFFIELD
Country: United Kingdom
Description: The oxygen reduction reaction (ORR) is critical in fuel cells (FC), batteries and corrosion. Sluggish kinetics of the ORR remains a key barrier to efficient electricity generation in FC operating on renewable fuels such as hydrogen or alcohols. Poor understanding of the ORR mechanism has hindered development of cost-effective and improved FC catalysts.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Country: United Kingdom
Description: Gastrointestinal infections have substantial impact in both the developing world and in Europe with 1.5 billion cases each year leading to approximately two million deaths each year, 760,000 of which are in children under five years old. Many of these deaths are caused by bacteria for example E. coli O157, that produces protein toxins, including shiga-like toxin (SLT). In the human body, the surfaces of living cells are covered in complex carbohydrate molecules. This “sugar coating” allows the cells to interact with viruses, bacteria, and toxins that have complementary protein receptors. The pentagonal shiga-like toxin produced by E. coli O157 bacteria can attach to five copies of a specific carbohydrate on the gut wall and enter cells lining the intestine. The result is bloody diarrhoea and the toxin entering the circulatory system to cause kidney failure.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF LEEDS
Country: United Kingdom
Description: The vision of 1D-NEON proposal is to develop fibre-based smart materials along with an integrated technology platform for the manufacturing in Europe of new products with multi-sectorial applications in consumer electronics, energy, healthcare and fitness, smart buildings, sensors and e-skin for soft robotics.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
Country: United Kingdom
Description: Balanced excitation and inhibition is a fundamental principle of neural circuit function, and perturbed excitation/inhibition (E/I) balance has been linked to diseases such as epilepsy, autism and schizophrenia. Maintaining E/I balance within normal bounds depends in part on homeostatic plasticity, in which neurons compensate for deviations in activity levels by adjusting their responsiveness to excitation and inhibition. Yet despite recent progress in elucidating molecular mechanisms underlying homeostatic plasticity in reduced preparations, little is known about such mechanisms in the intact brain.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF SHEFFIELD
Country: United Kingdom
Description: The challenges facing society in urban wastewater management cannot be solved by any one sector alone. ALICE (AcceLerate Innovation in urban wastewater management for Climate changE) will accelerate innovation by bringing together and exchanging knowledge between the key players who can, together, address the future techno-economic, governance and societal challenges arising from climate change. It will boost international and interdisciplinary skills, as well as careers perspective of Experienced Researchers, Early Stage Researchers, and the workforce of industry, water utilities and public organizations. The results will 1) benefit water utilities, 2) support political and managerial decisions in wastewater, 3) benefit wastewater equipment manufacturers, identifying new market opportunities in the EU, 4) benefit EU citizens from the improved wastewater infrastructure, the environment and job creations.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF ULSTER
Country: United Kingdom
Description: Liver disease incidence is increasing and about 170K patients die from liver failure each year in Europe. In liver failure, the accumulation of protein bound toxins and increased susceptibility to infection cause multiorgan failure and death. Liver transplantation is the only treatment known to prolong the life but is limited by availability of organs. A clinically efficacious ‘liver dialysis device’ is an unmet clinical need. The ALIVER Consortium has developed and optimised a novel ‘liver dialysis device’, DIALIVE. The DIALIVE device is protected by world-wide patents and is based upon our discovery that (i) albumin, a circulating protein involved in detoxification is reduced irreversibly in function and (ii) endotoxemia contributes to increased risk of infection in liver failure. DIALIVE incorporates albumin removal and replacement and, endotoxin removal and is a TRL5. In animal models of liver failure, DIALIVE was shown to be easy to use, safe, reduced endotoxemia and, improved albumin and immune function and, prolonged survival. The ALIVER Consortium, which is comprised of experts in liver failure, SMEs and charities proposes to perform clinical trials of DIALIVE in patients with acute on chronic liver failure (ACLF). During the grant period a CE-mark will be obtained and the device will progress to a TRL7/8. Consultation with Regulatory bodies confirms that if the trials are successful, a CE-mark is highly likely. Grifols, a large plasma proteins company is a potential licensee of the technology if the studies proposed by the ALIVER Consortium are positive.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY COLLEGE LONDON
Country: United Kingdom
Description: Fragment-based ligand discovery (FBLD) has become a mainstream strategy to discover new drugs to enable the treatment of conditions with unmet medical needs. Despite the remarkable rise of FBLD, significant chemical challenges remain in the field; firstly, elaborated fragments tend to be synthesised de novo when direct growth would be much more advantageous. Secondly, the currently available toolkit for fragment elaboration tends to exacerbate an uneven exploration of chemical space, yielding flatter and more lipophilic compounds.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF LEEDS
Country: United Kingdom
Description: MMbio will bridge the classically separate disciplines of Chemistry and Biology by assembling leading experts from academia and non-academic partners (industry, technology transfer & science communication) to bring about systems designed to interfere therapeutically with gene expression in living cells. Expertise in nucleic acid synthesis, its molecular recognition and chemical reactivity is combined with drug delivery, cellular biology and experimental medicine. This project represents a concerted effort to make use of a basic and quantitative understanding of chemical interactions to develop and deliver oligonucleotide molecules of utility for therapy. Our chemical biology approach to this field is ambitious in its breadth and represents a unqiues opportunity to educate young scientists across sectorial and disciplinary barriers. Training will naturally encompass a wide range of skills, requiring a joint effort of chemists and biologists to introduce young researchers in a structured way to and array of research methodologies that no single research grouping could provide. The incorporation of early-stage and later stag ebiotechnology enterprises ensures that commercialisation of methodologies as well as the drug development process is covered in this ITN. We hope that MMBio will train scientists able to understand both the biological problem and the chemistry that holds the possible solution and develop original experimental approaches to stimulate European academic and commercial success in this area.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
Country: United Kingdom
Description: BIOCLEAN addresses the urgent need to create a sustainable training network across academia, industry and the healthcare sector which will fill the gap in Europe and beyond to produce highly skilled multi-disciplinary young scientists competent in chemistry, engineering and experimental wet lab biology. BIOCLEAN will deliver this network of young scientists who can apply their proven skill sets gained during the project life time to solve industrial and healthcare sector real life biofilm management challenges.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: PROCTER & GAMBLE TECHNICAL CENTRES LIMITED
Country: United Kingdom
Description: Liver cancer in the paediatric population is rare with an incidence approximately 1-1.5 per million population. The commonest tumour seen in the childhood population is hepatoblastoma (HB), usually seen in young children and infants. Much rarer (about 10% of paediatric liver cancers) is hepatocellular carcinoma (HCC), usually seen in the teenage population and sometimes associated with underlying cirrhotic liver diseases. The ChiLTERN project relates to topic PHC 18 ‘establishing effectiveness of health care interventions in the paediatric population’. The ChiLTERN project builds on a unique opportunity to undertake a comprehensive research programme linked to an ambitious global partnership which will see the single largest clinical trial (the Paediatric Hepatic International Tumour Trial - PHITT) ever undertaken in this population of patients, with several randomised questions in six subgroups of patients. ChiLTERN will allow us to move towards an era of personalised therapy in which each patient will receive the correct amount of chemotherapy and will undergo has the best surgical operation (surgical resection or liver transplant). By using both clinical and biological information, we can assign patients more accurately to risk groups based on their survival. Using genetic tests and biomarkers, we will determine those children who may be at risk of developing long term side effects (deafness, heart failure, kidney damage). In addition, biomarkers will allow us to monitor during therapy and detect toxicities early before serious damage is done so that we can adapt treatment and prevent these problems. Finally, we will be using imaging technology tools which will help our surgeons plan liver operations more safely and effectively. Ultimately ChiLTERN will allow us to cure more children with liver cancer, expose fewer children to toxic chemotherapy and ensure their surgery is both effective and safe.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF BIRMINGHAM
Country: United Kingdom
Description: BOND acknowledges the fundamental role farmers and land managers play in the environmental and economic sustainability of the farming sector in Europe, as well as the importance of the way they organise, on Europe’s foods and landscapes. BOND contributes to unleash, strengthen, and organise, the great potential for collective action and networking of individuals, groups and entities of farmers and land managers, focusing on countries with lower organisation levels, with a view to creating strong, dynamic and effective organizations that have a voice and a place in policy design. More specifically, BOND investigates and addresses the constraints and disincentives, and reaches a higher level of participation of farmers as follows: (i) Draw up solutions and build bonding capital within groups, ensuring cohesiveness and trust among people; (ii) Enable organizations to come closer, building bridging capital to form larger networks, help overcome attitudes and constraints that impede collective action; (iii) Build linking capital, developing ties with entities with different interests and powers, including government, donors, academia, private sector, to reach a stronger position in decision-making, and (iv) Engage multi actors and policy makers throughout these processes. BOND’s approach relies on 3 pillars: SEE-learning from success (mobilisation, study tours), LEARN-overcoming constraints (self-analysis, capacity building), TELL-affirming a position in the policy landscape (gaming interface, best practice in regulation, lab experiment), and on involving the youth, women and men (designing a road map for the future), with training sessions and meeting events at every step of the project (interregional forum, national workshops, regional policy roundtables, youth forum). BOND’s legacy will be a menu a la carte of practical processes, user-friendly, with methods and tools to guide end-users when they decide to engage and benefit from the synergies of working with others.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: COVENTRY UNIVERSITY
Country: United Kingdom
Description: The subglacial environment beneath the Greenland and Antarctic ice sheets is one of the physically least well characterised environments on Earth. Ice sheet model simulations demonstrate high sensitivity to their basal sliding parameterisation which is governed by basal roughness, the thermal state of the bed, and lithology (presence or absence or deformable sediments). Compiling observations of the current state of the glacier bed is therefore crucial for the accuracy of ice sheet modelling and future predictions of sea level change. Radio-echo sounding (RES) is the only existing geophysical technique that has sufficient data coverage to enable ice-sheet-wide information to be obtained from the bed. In general, however, quantitative analysis of radar sounding data, and integration with electromagnetic and geostatistical approaches, lags significantly behind the data availability.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF BRISTOL
Country: United Kingdom
Description: While in the developed regions availability of electricity power has paved the way of sustainable development, it is still not available to ca. 18% of the world population, living in rural areas in developing countries and refugee camps worldwide. No access to power indicates exhausting effort for covering basic needs, which impedes sustainable social and economic development. Nearly 700 million people worldwide have mobile phone connections but no access to the electricity. In India, people belong to off-grid communities need to travel approximately 15 km to get their mobile phone charged. We have developed a unique solar power based Hub system and remote payment control mechanism by which electronic devices can be charged under the control of a central server to ensure accountability and transparency. This will enable EU companies to enter in €8 to 10 billion untouched market by delivering essential internet-based services (e.g., e-health, e-education, e-governance etc). BuffaloGrid supplies Hubs free of cost to local agents. This will stimulate local enterprise, encourage entrepreneurship and boost economic development. During SMEi Phase – 1 feasibility study, we have identified several technical improvements that are mainly focused on further development of the Hub, PCB and server designs. For commercial feasibility of the project, we have successfully performed market research, environmental impact assessment, partnership establishment, risk analysis and competitor analysis. During this project, we aim to reach from TRL7 to TRL9 and will make the product ready for mass scale deployment. We will focus on technical design improvement of the Hub for cost reduction (60%) and will finalise optimised system for mass scale production. We will also validate Hub functionality and server operations and will trial online services of EU SMEs in the field. Our commercialization plan is to deploy minimum 50,000 hubs across India, Sub-Sahara Africa and Refugee camps by 2021.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: BUFFALOGRID LIMITED
Country: United Kingdom
Description: C3-Cloud will establish an ICT infrastructure enabling a collaborative care and cure cloud to enable continuous coordination of patient-centred care activities by a multidisciplinary care team and patients/informal care givers. A Personalised Care Plan Development Platform will allow, for the first time, collaborative creation and execution of personalised care plans for multi-morbid patients through systematic and semi-automatic reconciliation of clinical guidelines, with the help of Decision Support Modules for risk prediction and stratification, recommendation reconciliation, poly-pharmacy management and goal setting. Fusion of multimodal patient and provider data will be achieved via C3-Cloud Interoperability Middleware for seamless integration with existing information systems. An Integrated Terminology Server with advanced semantic functions will enable meaningful analysis of multimodal data and clinical rules. Active patient involvement and treatment adherence will be achieved through a Patient Empowerment Platform ensuring patient needs are respected in decision making and taking into account preferences and psychosocial aspects. Co-design and 4-layered multi-method multi-stakeholder evaluation will lead to a user friendly solution. To demonstrate feasibility, pilot studies will focus on diabetes, heart failure, renal failure, depression in different comorbidity combinations. Pilots will operate for 15 months in 3 European regions with diverse health and social care systems and ICT landscape, which will allow for strengthening the evidence base on health outcomes and efficiency gains. C3-Cloud adaptive patient pathways and organisational models validated by patient organisations and a clinical reference group, change management and training guidelines will be shared with the European community. Commercial exploitation of C3-Cloud integrated care solutions will be facilitated through an Industry Vendor Forum and commercial EHR/PHR products of 3 leading SMEs.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF WARWICK
Country: United Kingdom
Description: Chronic liver disease affects about 29-million Europeans accounting for about 170,000 deaths at a cost of around €15.8bn. This chronic non-communicable disease is increasing at an alarming rate due to increasing European obesity, alcohol use and ageing. The three main causes of the disease; alcohol, fatty liver and viral hepatitis are amenable to prevention and treatment. Gut-derived endotoxins and bacterial translocation are central factors implicated in the pathogenesis of fatty liver disease and, the development and progression of cirrhosis. In cirrhosis, current state-of-the-art therapy to prevent recurrent complications of advanced cirrhosis is to use poorly absorbed antibiotics but long-term antibiotic therapy has problems associated with bacterial resistance, infection with resistant organisms and the cost. Treatment of fatty liver and modulation of bacterial translocation in early cirrhosis to prevent complications is an unmet need. Our academic-industrial consortium has developed a novel, patented, safe and cheap nanoporous carbon that modulates the effects of bacterial translocation in animal models of liver disease. Our feasibility studies demonstrate that this product advances the current state-of-the-art, is a TRL 4/5 and is now ready for validation through clinical trials. We propose to investigate the safety and efficacy of this novel nanoporous carbon in patients with fatty liver disease and cirrhosis. If successful, we will be able to confirm an innovative, cost-effective and novel strategy for the management of this chronic disease in a European population. Exploitation of the results of the CARBALIVE project will support the continued development of this carbon through additional private and public sector investment. The use of this innovative therapy is expected to reduce the economic burden of the disease in Europe, allow patients to achieve enhanced quality of life, improve survival, and allow many patients to return to economic productivity.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY COLLEGE LONDON
Country: United Kingdom
Description: In this project, the fabrication and characterisation of all diamond superconducting Nano-Electro-Mechanical Systems (NEMS) is proposed for the investigation of macroscopic quantum states. This involves state of the art Chemical Vapour Deposition (CVD) of diamond, doping, nanofabrication and modelling of devices. The fundamental properties of superconducting diamond, the associated mechanical properties of diamond NEMS and the characterisation of low temperature and low dimensional quantum effects will be investigated.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: CARDIFF UNIVERSITY
Country: United Kingdom
Description: Estrogen Receptor (ER) is the driving transcription factor in ~75% of all breast cancers. ER antagonists are routinely used for treatment, but significant variability exists in clinical response. We are interested in explaining this heterogeneity and exploiting the mechanistic insight. We have recently identified important, but previously uncharacterised cross-talk between ER and the progesterone receptor (PR) and androgen receptor (AR) pathways, both of which are commonly expressed in ER\ tumours. Recently, ER has been shown to be mutated in ~18-55% of metastatic breast cancers. In addition, two key ER-chromatin regulatory proteins, FoxA1 and GATA3, are mutated in primary ER\ disease. Finally we have discovered three previously unknown phosphorylation events on FoxA1.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
Country: United Kingdom
Description: CHARIOT will provide a design method and cognitive computing platform supporting a unified approach towards Privacy, Security and Safety (PSS) of IoT Systems including the following innovations:
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: INLECOM SYSTEMS LTD
Country: United Kingdom
Description: The CO2 Human Emissions (CHE) project will coordinate efforts towards developing a European monitoring capacity for anthropogenic CO2 emissions. This challenging target is aligned with the European Commission’s stepwise approach for a requirement-driven integration of Earth observations, from remote sensing and in situ, with enhanced modelling capabilities for CO2 fossil fuel emissions, along with other natural and anthropogenic CO2 emissions and transport. The project will pursue a consolidated methodology for integrating the monitoring system components, as well as innovation for estimating fossil fuel CO2 fluxes. These include reconciling bottom-up and top-down constraints and handling systematic errors of satellite sensors. Earth observations from satellites will be combined with in situ CO2 observations and information from co-emitters or isotopes to support the attribution of fossil fuel emissions and uncertainty reduction. Methodological advances will include a representation of anthropogenic CO2 variability in space and time, responding to documented shortcomings and needs, and a carbon cycle data assimilation system extended to enable estimates of emission uncertainties. Strategies to separate anthropogenic CO2 emissions from biogenic fluxes at country to global scales using observations and models will be documented. CHE will support a large community by providing a library of realistic CO2 simulations from global to city scale to examine the capacity for monitoring future fossil fuel emissions and to adequately dimension space mission requirements. Community building will include direct collaboration across 22 European institutions, and communication and liaison with key European and international stakeholders. These coordination efforts will ensure the transfer of science and technology requirements and recommendations for strengthening existing assets with a view to developing an anthropogenic CO2 monitoring service.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS
Country: United Kingdom
Description: Riveting is the defacto method for the assembly of aluminium aerostructures, with large commercial aircraft fuselages typically containing 100’000s of rivets. However, riveting is known as a time-consuming, expensive and weight-adding operation. From a design perspective, it also places holes and point loads in a cyclically pressurised structure, subject to long-term fatigue loading and corrosion. Thus is not an ideal solution for these types of structures.
Loading Wayback Capture Info...
Loading video data...
Description: The Climateurope Action will coordinate and support Europe’s knowledge base to enable better management of climate-related risks and opportunities thereby creating greater social and economic value. Climateurope has four main objectives:
Loading Wayback Capture Info...
Loading video data...
Description: The rapid increase in data traffic in the past years and traffic forecasts will lead to capacity exhaust in the optical fibre communications infrastructure which carries over 95% of all data services. The optical fibre channel is nonlinear, that is, its properties, namely its refractive index, is dependent on optical intensity, and at high power densities, the combination of nonlinear effects and dispersion leads to nonlinear distortion, limiting both achievable capacities, spectral efficiencies and distances. A key research area requiring investigation is nonlinear coding and detection, tailored to the nonlinear channel to dramatically improve the data throughput of future optical networks. New R&D is critically needed not only for finding new native nonlinear communication techniques but also transferring them into practical, error-resilient systems. The COIN objective is, thus, the development of a new area of nonlinear communications including forward error correction, essential for reliable communication. Specifically, COIN will investigate the application of nonlinear Fourier transforms and nonlinearity-tailored coding and detection by effectively integrating the scientific expertise of the key academic research groups in information theory, coding, coherent optical communication and high-speed transmission with the industrial know-how of the consortium. The COIN R&D goals will be to focus on the development of new, native communication schemes and waveforms alongside with the development of coding schemes for these and existing non-linear Fourier transform based transceivers. The R&D tasks will be carried out along with researcher training in the leading scientific centres in Europe. The PhD training programme is designed to maximize the unique synergy between the collaborators to promote career opportunities of the COIN researchers in ICT, generating new types of key expertise and and human capital for the European Research Area.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY COLLEGE LONDON
Country: United Kingdom
Description: Industries are in need of highly skilled academically trained experts and powerful sets of tools enabling the design, control & prediction of optimized & efficient production process of future high-value products such as chiral pharmaceuticals. The CORE Network will in parallel train 15 ESRs and develop tools, approaches and methods within the area of Continuous Resolution (CORE), the process to obtain enantiopure molecules of chiral compounds.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF STRATHCLYDE
Country: United Kingdom
Description: Semantic search engines use structured knowledge to improve traditional web search, e.g. by directly answering questions from users. Current approaches to semantic search rely on the unrealistic assumption that all true facts about a given domain are explicitly stated in their knowledge base or on the web. To reach their full potential, semantic search engines need the ability to reason about known facts. However, existing logics cannot adequately deal with the imperfect nature of knowledge from the web. One problem is that relevant information tends to be distributed over several heterogeneous knowledge bases that are inconsistent with each other. Moreover, domain theories are seldom complete, which means that a form of so-called plausible reasoning is needed. Finally, as relevant logical theories do not exist for many domains, reasoning may need to rely on imperfect probabilistic theories that have been learned from the web.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: CARDIFF UNIVERSITY
Country: United Kingdom
Description: Customem Ltd is a company founded in 2014 with the long term vision to harness nature’s capacity to make biomaterials to promote human health in alignment with sustainable development goals.A next generation nanomedia that can be tailored to capture and recycle specific micropollutants in contaminated industrial waste dischargeLack of access to clean water is predicted to affect 47% of the world’s population by 2030. Contamination of water supplies by micropollutants such as metal ions, pesticides and pharmaceuticals is a major contributor to this water stress. These pollutants are released by industrial processes in the textile and manufacturing industries. Existing water treatment removes 99.96% of contaminants, but does not remove the 0.04% of micropollutants. Although the remaining contaminants seem small, they are a major problem as they are exceptionally difficult to capture but also highly toxic to humans and animals. CustoMem have developed a customisable selective nanocellulose media called CustoMem Granular Media (CGM) that is bioengineered to capture and remove all micropollutants including the 0.04% that cannot currently be removed.Customers benefit from a simple, low cost, low energy solution that is low maintenance. It allows removal of all micropollutants resulting in clean water supplies. The company is headquartered in the Imperial College Incubator UK and employ 5 full time employees and multiple subcontractors. The company is currently in talks with companies in the EU who have shown an active interest in the project.
Loading Wayback Capture Info...
Loading video data...
Description: Current medical teaching practice is still largely based on textbooks and lectures. Students struggle to get access to relevant
Loading Wayback Capture Info...
Loading video data...
Description: DemoWind 2 proposes to bring together a number of national and transnational organisations with an interest in accelerating cost reduction in offshore wind. It follows on from the first DemoWind initiative that launched in 2014 and, like its predecessor, is focussed on enabling industry, through partnership, to push technologies through TRLs 5-6 to 6-7 in transnationally funded projects. We aim to connect existing and new European offshore wind demonstration opportunities, exchange knowledge and facilitate the acceleration of cost reducing innovative technologies to commercialisation.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: DEPARTMENT FOR BUSINESS ENERGY AND INDUSTRIAL STRATEGY
Country: United Kingdom
Description: The worldwide demand for metals and rare-earth elements is increasing, fuelled by developing economies and the growth of high-technology green industries. The Clarion-Clipperton Zone (CCZ) in the tropical eastern Pacific Ocean contains vast reserves of polymetallic nodules on the abyssal seafloor, a future source of deep-sea minerals already targeted for exploitation. There is an almost complete absence of open biodiversity data on the large animals (megafauna) of this 6 million km2 area, and it is a pressing conservation priority to establish baseline data to enable future sustainable management of the region. In particular, a regional-level assessment that cuts across contracted areas is urgently needed to [1] establish the baseline quantitative ecology of the region, [2] assess species richness and ranges and thus, [3] enable the successful management of this globally important marine area in the context of a global ‘blue growth’ agenda. The objective of this fellowship is to develop the first regional-level approach to megafauna classification and identification in the CCZ. This will be done using a three-fold approach: (1) The development of a new open-access data-archiving bioinformatic pipeline for imagery and samples of megafauna from the entire CCZ, (2) the identification and characterization of megafaunal morphotypes observed across the CCZ regardless of exploration contract area and (3), development of biodiversity survey methods based on organismal DNA found in the environment (metabarcoding). This project will include knowledge transfers between the host and experienced researcher in the following areas: bioinformatics, digitisation, image analysis, megafauna taxonomy, DNA barcoding, metagenomics and transferable skills such as project management, scientific communication including science-policy interface work, laboratory health and safety, and career planning.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: NATURAL HISTORY MUSEUM
Country: United Kingdom
Description: Communication strategy and tools for optimizing the impact of Ebola vaccination deployment.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER
Country: United Kingdom
Description: Due to an aging population and the spiralling cost of brain disease in Europe and beyond, EDEN2020 aims to develop the gold standard for one-stop diagnosis and minimally invasive treatment in neurosurgery. Supported by a clear business case, it will exploit the unique track record of leading research institutions and key industrial players in the field of surgical robotics to overcome the current technological barriers that stand in the way of real clinical impact.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Country: United Kingdom
Description: OCTARRAY is part of an an ambitious 3-year tidal array demonstration programme located in North Western French territorial waters of the Raz Blanchard, a 15 km strait situated between Cap de la Hague and Alderney Island. The array (known as the Normandie Hydro array) will consist of 7 x 2.0MW Open-Centre Turbines (OCT) designed and constructed by the OpenHydro Group which will be installed at depths of between 30 and 40 meters with a total capacity of 14MW. The turbines will be connected by inter-array cabling via a subsea connector and exported onto the grid via an export cable and substation. The project is scheduled to commence operations and begin exporting grid compliant power to the French National Grid in 2019. The objectives of the project are to develop, construct and operate a tidal turbine array in real conditions and to test and confirm the technical and economic viability of tidal energy in preparation for developments on an industrial and commercial scale. The successful demonstration of the pilot array will achieve several technical, industrial, economic and commercial ‘firsts’ which will facilitate and accelerate the development and growth of the tidal industry. OCTARRAY will establish new knowledge and capability to enable the scale up to future commercial arrays (up to 300MW), Levelised Cost of Energy reduction and will provide valuable data and learning on array effects and performance for the benefit of future tidal array projects in the rest of Europe and strategic locations in the world for renewable energy development. Through projects such as OCTARRAY and the Normandie Hydro array, Europe has the opportunity to significantly build its reputation as a world leader in the development and integration of tidal energy, and benefit from the diversity that the technology brings to the overall energy generation portfolio.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE EUROPEAN MARINE ENERGY CENTRE LIMITED
Country: United Kingdom
Description: EmERGE will develop a mHealth platform to enable self-management of HIV in patients with stable disease. The platform will build upon and integrate the existing mHealth solutions operated by pioneering healthcare providers in the UK and Spain and apply a rigorous co-design approach to ensure patient and clinician input to the solution. The platform will provide users with web based and mobile device applications which interface securely with relevant medical data and facilitate remote access to key healthcare providers EATG, the European HIV patient organisation, will provide a direct and deep interaction with representative patients and clinicians from 5 EU countries. The platform and interfaces will be validated in a large study of 3900 patients using a tailored HTA process, MAST, specifically developed for the assessment of mHealth solutions including translatability as a key factor. Based on prior work showing a high uptake rate and use of mHealth in HIV patient populations, EmERGE aims to demonstrate the benefits to patients and simultaneous increases in cost-effectiveness for healthcare providers by reducing face-to-face consultations, estimated at 6000 saved per year within this study alone. Patient reported outcomes will be agreed and used in the assessment and development of the system which also aims to increase adherence and enable frailty to be reported using mHealth technology. Innovation will be given priority from the beginning by developing new business models of care provision, targeting key stakeholders in the EU health provider sector, including policymakers and clinicians, while eliciting demand from patients to highlight and initiate the widespread implementation and compensation of mHealth solutions within the timeframe of the project. Guidelines and policy briefs will be produced to evidence the benefits and disseminate the lessons learned to support the uptake of mHealth for self-management of other chronic diseases.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: BRIGHTON AND SUSSEX UNIVERSITY HOSPITALS NHS TRUST
Country: United Kingdom
Description: The objective of this proposal is to implement a programme of research and impact activities intended to provide a step change in the level of understanding of, and modelling capacity for, spatially disaggregated temporal domestic electricity demand in a smart grid and demand response context. This programme will be developed in partnership with internationally recognised experts led by the University of Otago (host) who are pioneering in this field. It will be exploited via an applied research programme at the University of Southampton (beneficiary) which intends to integrate census, social science time use and detailed consumption data to develop local area level demand response models to support the analysis of a range of demand response scenarios. In so doing the fellowship will provide the applicant with a foundation from which to build a new career pathway by applying his substantial existing social scientific data analysis and spatial microsimulation expertise to the development and leadership of a substantial new European research capacity in an area of emerging commercial, societal and political significance.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF SOUTHAMPTON
Country: United Kingdom
Description: A significant step change is proposed in the way virtual and test environments are used together in an industrial environment to reduce the cost, risks and time associated with product development. Enabling technologies, which have been demonstrated in laboratory conditions during a series of EU FP 5 and 7 projects, will be transitioned into the industrial environment and demonstrated in a structural test on an aircraft subcomponent. In more detail: approaches to quantifying uncertainty in measurements of displacement and strain fields obtained using digital image correlation will be reviewed and a simple-to-use, robust methodology developed for use in industrial environments, with attention paid to the need to consider the entire measurement volume as well as within the same timescale as a structure test. In addition, recent advances in the validation of simulations, using image decomposition to compare predicted and measured data fields, will be incorporated into advanced structural test protocols taking account of uncertainties to provide statements on the extent to which the predictions represent reality, i.e. the validity of the simulations. Best practice guidelines will be developed to allow the test matrix to be optimised thus minimizing the cost and time required for tests while maximising the reliability and credibility of the simulations. The proposed research represents a significant and generic advance in the technologies and methodologies used to validate computational models of structures that will benefit a wide range of industrial sectors, including the aerospace industry where it will support the introduction of disruptive technologies, such as highly integrated structures, by enabling high fidelity simulations. A strong programme of exploitation and dissemination is proposed using traditional routes as well as digital shorts, webinars, and a blog as well as workshops linked to the revision of the prenormative document published by CEN.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF LIVERPOOL
Country: United Kingdom
Description: Pharmaceutical industry, as well as basic science, depend on robust data and scientific rigor as key drivers for decision making, patent strength and time-to-market, which in turn will determine knowledge gain and availability of new treatments to patients. Recent publications report challenges with the robustness, rigor, and/or validity of research data, which may impact decisions about whether to proceed to preclinical and clinical testing as well as conclusions on the predictability of preclinical models. There is a need for simple, sustainable solutions that facilitate data quality.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF EDINBURGH
Country: United Kingdom
Description: We propose a Multi-Partner ITN-ETN network on Transport of Soft Matter at the Nanoscale. The scientific topic, which is the focus of the proposal, is an emerging field of science and technology. Challenges such as design of environmentally friendly engineering materials or understanding the principles of biological organization crucially depend on fundamental understanding of transport of fluids and colloids at the nanoscale. Topics we will study within NANOTRANS are at the core of modern technology (i.e. active design of “smart” nanomaterials, nanofluidic and “lab on a chip” devices, sustainable nanocompounds, energy storage, contaminants dissemination in environment, oil recovery, drug delivery and disease treatment).
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
Country: United Kingdom
Description: ATLAS creates a dynamic new partnership between multinational industries, SMEs, governments and academia to assess the Atlantic’s deep-sea ecosystems and Marine Genetic Resources to create the integrated and adaptive planning products needed for sustainable Blue Growth. ATLAS will gather diverse new information on sensitive Atlantic ecosystems (incl. VMEs and EBSAs) to produce a step-change in our understanding of their connectivity, functioning and responses to future changes in human use and ocean climate. This is possible because ATLAS takes innovative approaches to its work and interweaves its objectives by placing business, policy and socioeconomic development at the forefront with science. ATLAS not only uses trans-Atlantic oceanographic arrays to understand and predict future change in living marine resources, but enhances their capacity with new sensors to make measurements directly relevant to ecosystem function. The ATLAS team has the track record needed to meet the project’s ambitions and has already developed a programme of 25 deep-sea cruises, with more pending final decision. These cruises will study a network of 12 Case Studies spanning the Atlantic including sponge, cold-water coral, seamount and mid-ocean ridge ecosystems. The team has an unprecedented track record in policy development at national, European and international levels. An annual ATLAS Science-Policy Panel in Brussels will take the latest results and Blue Growth opportunities identified from the project directly to policy makers. Finally, ATLAS has a strong trans-Atlantic partnership in Canada and the USA where both government and academic partners will interact closely with ATLAS through shared cruises, staff secondments, scientific collaboration and work to inform Atlantic policy development. ATLAS has been created and designed with our N American partners to foster trans-Atlantic collaboration and the wider objectives of the Galway Statement on Atlantic Ocean Cooperation.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF EDINBURGH
Country: United Kingdom
Description: The European Union (EU) is the world’s second biggest producer of pigmeat and is the market’s largest exporter. In order to maintain an economically viable and sustainable pig industry, innovation is a key factor. EU PiG specifically aims to more effectively connect producers with the latest science, husbandry techniques and technologies from within their industry via fellow producers, academics and advisors connected through thematic and regional platforms. A unique consortium of 19 organisations has been brought together, representing 13 Member States that together account for 92% of the EU’s pig meat production and 89% of the EU’s pig herd in 2014. The EU PiG consortium represents a wide range of ‘actors’, including national and regional pig producer groups, researchers, rural development boards, innovation practitioners and SMEs. EU PiG will provide a platform for dialogue for the actors, facilitating the exchange of knowledge and sharing of innovative best practice.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE AGRICULTURE AND HORTICULTURE DEVELOPMENT BOARD (AHDB)
Country: United Kingdom
Description: Big data and data analytics offer significant opportunities to transform Research and Innovation (R&I) policy with a new generation of more relevant, inclusive and timely indicators than those already available, potentially enabling better decisions with bigger (and better measured) impacts. However, concerns about the representativity, accuracy and interpretability of new data sources and methods is slowing down their acceptance.
Loading Wayback Capture Info...
Loading video data...
Description: The overarching objective of Farmer’s Pride is to establish a network of stakeholders and conservation sites that effectively coordinates conservation actions to safeguard the wealth of Europe’s in situ plant genetic resources (PGR) and integrates the user community to maximize their sustainable use. Specifically, to address the challenge and scope of the SFS-04-2017 work programme, Farmer’s Pride will: a) build relationships between existing diverse PGR stakeholder networks, and where necessary create new partnerships to establish a unified network of stakeholders involved in PGR conservation and sustainable use; b) enhance existing knowledge of European landrace and crop wild relative genetic diversity and showcase how it can be effectively secured and managed; c) use social science and economic tools to establish the value of in situ PGR populations and individual traits, as well as a cost effective means of conserving them; d) use predictive characterization methods to identify valuable traits in in situ PGR populations, targeting those most vital for satisfying future agricultural and market needs; e) establish a mechanism to facilitate the flow of plant genetic material from in situ populations to the user community, both directly and via ex situ collections; f) develop and establish a durable governance and resourcing structure for the European network of in situ PGR conservation sites and stakeholders; g) promote public awareness of the value of PGR for agriculture and consumers; and h) design and implement a network of European sites and stakeholders that conserves the breadth of PGR diversity found in situ. Through these activities, Farmer’s Pride will result in significant strengthening of European capacities for the conservation, management and sustainable use of in situ PGR as a foundation for increased competitiveness in the farming and breeding sectors, and ultimately for long-term food and nutritional security in Europe.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF BIRMINGHAM
Country: United Kingdom
Description: Sports injuries can result in an immense amount of long-term pain and suffering to the lives of those effected and even results in fatalities. This also results in a huge burden on EU hospitals, who spend €2.4 billion a year in direct health costs to treat patients effected by sports injuries. Horse riding is a particularly dangerous sport as the actions of horses can be unpredictable, making serious injury and fatality a possibility each time a rider mounts a horse. Chest and spinal injuries contribute to up to 26% of hospital admissions for horse riding accidents and injuries to both the body and shoulder are common in other dangerous sports such as mountain biking and snowsports.
Loading Wayback Capture Info...
Loading video data...
Description: 'FUTURES: Create. Imagine. Explore. will bring together learning from the past and visions of the future by celebrating cultural heritage and exploring innovation. We will achieve this by hosting two nights of activities across the cities of Bristol and Bath engaging the South West region in a celebration and discovery of European cutting-edge research and its place in society.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF BRISTOL
Country: United Kingdom
Description: Due to its fundamental regulatory role, molecular recognition has been extensively studied by both experiments and
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY COLLEGE LONDON
Country: United Kingdom
Description: GETM3 – Global Entrepreneurial Talent Management 3 - focuses on young talent as a key driver of future development, developed through co-operation of 3 stakeholders: employers (inc MNC & SME’s), universities and students/graduates. Despite a widely recognized importance of young talent (e.g. Europe 2020), its potential remains largely untapped. They are educated and entrepreneurial and yet experience instability in employment. At the same time, employers report skills mismatch and difficulties with attracting, managing and retaining young talent. To tackle this paradoxical situation, an innovative, multi-perspective approach is needed, reinforced by our 15 partner consortium; comprising of a transnational, inter-disciplinary, inter-generational, gender balanced and inter-sectorial research team.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE
Country: United Kingdom
Description: The GLAUrious project is promoting the novel External Automatic Glaucoma Laser (EAGLE) device with the goal of providing accessible first-line treatment for glaucoma.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE QUEEN'S UNIVERSITY OF BELFAST
Country: United Kingdom
Description: Fuel cells have shown great promise for residential micro-Combined Heat and Power (mCHP) generation due to their high electrical efficiency and ability to run on conventional heating fuels. Technology leaders in this sector are nearing commercial deployment following extensive field trials but high capital costs remain a key challenge to the advancement of this sector and mass market introduction in Europe. The HEATSTACK project focuses on reducing the cost of the two most expensive components within the fuel cell system; the fuel cell stack and heat exchanger, which together represent the majority of total system CAPEX. Cost reductions of up to 60% for each component technology will be achieved by:
Loading Wayback Capture Info...
Loading video data...
Description: The project aims is focused on the design and manufacture of a novel air-oil engine cooling system to be integrated into the engine bay. The project will investigate any better configurations to achieve the same heat rejection with lower weight and smaller overall dimensions than conventional ACOC systems. In addition, improved integration into the engine system (without impairing cooler efficiency) will be designed through the use numerical simulations via Computational Fluid Dynamics (CFD) to assess the hydraulic, structural and aerodynamic impact of the ACOC installation. In addition to this an assessment of the heat management for the engine system will be required using 1D AMESIM simulation leading to a proposed heat management model and finally demonstrator hardware will be delivered for engine ground tests
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: HS MARSTON AEROSPACE LIMITED
Country: United Kingdom
Description: The current mining paradigm promotes extraction from large ‘world-class’ deposits that have required innovations in mining techniques to deal with low grades, large infrastructure to deal with high throughputs and large feasibility studies to prove long-term commercial viability. High investment in operations is no longer available in the current economic climate and many small companies have ceased to trade, concentrating production and limiting the ability of the raw materials market to respond to increased demand for raw materials or shortages in raw material supply. The problem is most extreme for critical raw materials that are produced in small quantities relative to traditional metal commodities because the potential return on investment is too low. The IMPaCT project proposes a solution that develops a new switch on-switch off (SOSO) mining paradigm to improve the viability of many critical metal and other small complex deposits.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF EXETER
Country: United Kingdom
Description: Available risk assessment frameworks typically consider individual assets of the transportation infrastructure, exposed to just one hazard and they neglect changes in the asset performance during its life. However, assets exist in systems (SoA) and they are usually exposed to multiple hazards, whilst their performance changes due to deterioration or improvements. Also, the vast majority of existing studies is qualitative and focuses on bridges. Hazards, such as ground movements, debris flow, earthquakes and floods are major threats to infrastructure around the world, causing significant physical and socio-economic losses. Thus, reliable assessment of the vulnerability and the associated risks of infrastructure subjected to critical hazards is of paramount importance toward resilient transportation networks. TRANSRISK aims to fill these acknowledged gaps and provide advanced vulnerability assessment of critical transportation SoA subjected to diverse geo- and climatic hazards with focus on geotechnical effects, taking into account the SoA performance changes during their life. In this context, advanced numerical models of representative SoA subjected to critical combinations of hazard effects will be generated and validated based on recorded events. Novel adaptable vulnerability models will be produced for as-built, deteriorated (e.g. past hazards) and improved (e.g. strengthened) SoA. These models will be applied to selected parts of a highway and/or railway network in Europe to estimate the risk and associated losses due to recorded hazards as a means to enable the unbiased allocation of resources in decision-making and disaster management. The research results will provide a better understanding of the response of critical SoA and a rational link of the individual asset response to the network performance. The outcomes will also benefit stakeholders and owners of transportation networks in line with the EU strategy on critical infrastructure protection.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF SURREY
Country: United Kingdom
Description: 'Agricultural production in Europe has significantly damaged soil and water resources, ecosystem biodiversity, socio-economic well-being and contributed to climate change. Expected further intensification of production to ensure food safety for population growth must be sustainable to minimise future impacts and negative externalities. This ETN addresses these challenges by training 15 early stage researchers in cutting edge research skills and innovative approaches to manage soil and groundwater impacts from agriculture for sustainable intensification. It supports EU policy goals on food security, resource conservation, renewable energy and climate change, and the aims of the H2020 Societal Challenge 5 Work Programme for sustainable management of the environment and its resources. The scientific objectives focus on developing (1) management techniques which mitigate environmental impacts of agricultural practices on soil, water and climate systems, and support sustainable intensification using new production methods; (2) 'smart' environmental monitoring, biotechnology and modelling tools to predict the outcome of measures and practices in (1); (3) decision-making tools with sustainability indicators to implement sustainable agricultural production methods. This will be achieved by linking lab-scale studies of processes with field-scale evaluation of novel management concepts, analytical tools and modelling, using state-of-the-art methods. The network includes research, advisory and commercial organisations from all sectors of the agri-environmental management community, and SMEs to multinational firms. Its novel training agenda of workshops and summer schools on technical and business skills, international conferences, industry secondments and knowledge transfer activities has the specific aim of transferable skills training. This is highly relevant for scientific communication, societal impact and entrepreneurship, preparing the fellows for careers in many sectors.'
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF SHEFFIELD
Country: United Kingdom
Description: Instruct-Ultra aims to advance the scope and efficiency of implementation of Instruct and consolidate the foundations for long-term sustainability. This will be achieved through specific objectives: expand Instruct membership to new Member States and increase global links; engage new user communities; improve efficiencies in service delivery; improve data capture and management; adjust the scale and reliability of the infrastructure. Instruct-Ultra will deliver these alongside the transition to ERIC legal status and rapid developments in, and increased demand for, integrated structural biology infrastructure. These advances in the scale and speed of delivery will earn further trust within the life science community. One focus will to expand membership to Eastern European states and EFTA countries, integrating their structural biology communities into Instruct and providing new opportunities to support research excellence and raise standards. Opportunities for engaging with industrialised and developing countries outside the ERA will build on existing cooperative work between Instruct and Asian, African and South American countries to establish strong bilateral programmes of benefit to both parties, giving Instruct better engagement in emerging global challenges and positioning Instruct as a trusted global resource for high quality structural biology services. Starting from baseline operations four years ago Instruct has now identified key areas of service which should be expanded, new potential user groups, and opportunities for more reliable, efficient and sometimes remotely used workflows. Instruct-Ultra will therefore test new modes of access and pilot new service methods in high demand areas to accelerate access for more users. Instruct-Ultra will reinforce Instruct operations by updating and expanding the business plan and structural biology roadmap, whilst improving the interface with academia and industry as a strategy to sustainability.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: INSTRUCT ACADEMIC SERVICES LIMITED
Country: United Kingdom
Description: INTCATCH will instigate a paradigm shift in the monitoring and management of surface water quality that is fit for global waters in the period 2020-2050. INTCATCH will do this by developing efficient, user-friendly water monitoring strategies and systems based on innovative technologies that will provide real time data for important parameters, moving towards SMART Rivers. The business model will transform water governance by facilitating sustainable water quality management by community groups and NGOs using a clouds data linked to a decision support system and eco-innovative technologies.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: BRUNEL UNIVERSITY LONDON
Country: United Kingdom
Description: Short Bowel Syndrome (SBS) is a condition that occurs when part or the entire small intestine is missing or has been removed during surgery. This condition renders the bowel incapable of fulfilling its nutritional function (intestinal failure). There is no cure for SBS. Parenteral (intravenous) nutrition (PN) and bowel transplantation are currently the preferred options for nutrition in children and adults who have lost their bowel. PN offers a low survival rate, compromised quality of life, and the economic cost for each patient is estimated to be 55,000 euro/year. Small intestinal transplant is also an option with one-year and 4-year survival rates of 90% and 60% respectively. However, because of the shortage of organs, high mortality, the severe side effects of immunosuppression and low quality of life, this is still a sub-optimal solution.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY COLLEGE LONDON
Country: United Kingdom
Description: Waste heat recovery systems can offer significant energy savings and substantial greenhouse gas emission reductions. The waste heat recovery market is projected to exceed €45,0 billion by 2018, but for this projection to materialise and for the European manufacturing and user industry to benefit from these developments, technological improvements and innovations should take place aimed at improving the energy efficiency of heat recovery equipment and reducing installed costs. The overall aim of the project is to develop and demonstrate technologies and processes for efficient and cost effective heat recovery from industrial facilities in the temperature range 70°C to 1000°C and the optimum integration of these technologies with the existing energy system or for over the fence export of recovered heat and generated electricity if appropriate. To achieve this challenging aim, and ensure wide application of the technologies and approaches developed, the project brings together a very strong consortium comprising of RTD providers, technology providers and more importantly large and SME users who will provide demonstration sites for the technologies. The project will focus on two-phase innovative heat transfer technologies (heat pipes-HP) for the recovery of heat from medium and low temperature sources and the use of this heat for; a) within the same facility or export over the fence; b) for generation of electrical power; or a combination of (a) and (b) depending on the needs. For power generation the project will develop and demonstrate at industrial sites the Trilateral Flash System (TFC) for low temperature waste heat sources, 70°C to 200°C and the Supercritical Carbon Dioxide System (sCO2) for temperatures above 200°C. It is projected that these technologies used alone or in combination with the HP technologies will lead to energy and GHG emission savings well in excess of 15% and attractive economic performance with payback periods of less than 3,0 years.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: BRUNEL UNIVERSITY LONDON
Country: United Kingdom
Description: Recent research suggests that to control bodily movements the brain relies on Bayes-optimal predictive models that are updated by sensory prediction error. This assumption may be generalised within a new formal account of motor control as active (Bayesian) inference. Active inference explains motor control in terms of hierarchical Bayesian filtering or predictive coding, i.e., as belief updating and suppression of prediction error to optimise a hierarchical generative model in the brain; thereby the weighting of prediction errors by their predicted precision determines their relative impact on hierarchical inference. This novel proposal still lacks concrete empirical investigation. The proposed project will close this research gap by testing whether cortical information flow during manual actions, requiring visuomotor adaptation and cognitive control of attention, follows the principles of active inference. In two fMRI experiments and one MEG experiment, participants will move a photorealistic virtual hand model via an MR-compatible data glove to perform simple manual tracking tasks in a virtual reality environment. The precision of prediction errors at multiple levels of a previously established cortical motor control hierarchy will be experimentally manipulated via visuoproprioceptive conflicts (introduced by delayed visual movement feedback) and via attentional allocation – either stimulus-driven (via increased sensory noise) or endogenous (instructed) – to visual or proprioceptive movement feedback. Active inference’s specific predictions about information flow between and within cortical areas will be tested with recently established dynamic causal modelling of the modelled hemodynamic (fMRI) or spectral (MEG) responses. Active inference appeals to a general free-energy principle of brain function; this contribution will thus promote interdisciplinary exchange of knowledge about self- and world-representation in the brain and will be of general public interest.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY COLLEGE LONDON
Country: United Kingdom
Description: Are financial markets informationally efficient? Are some economic agents more informed than others? What is the impact of such heterogeneity on asset prices? These questions, of great economic significance, have permeated academic and business circles over the last few decades. Despite significant progress on the theoretical and empirical fronts relatively little is known about how information is endogenously acquired and processed in markets by agents with differential access to information and facing heterogeneous opportunities.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Country: United Kingdom
Description: The only lands on Earth that have not been explored in any depth by science are those that have been lost to the oceans. Global warming at the end of the last Ice Age led to the inundation of vast landscapes that had once been home to thousands of people. These lost lands hold a unique and largely unexplored record of settlement and colonisation linked to climate change over millennia. Amongst the most significant is Doggerland.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: UNIVERSITY OF BRADFORD
Country: United Kingdom
Description: The proposed research explores experiences of urban space among young indigenous Mapuche living in Santiago de Chile, in order to make visible indigenous subjects whose daily lives, collective concerns and social circumstances are often relegated to the margins of policy making and public interest. It seeks to research the impact of displacement and social exclusion on indigenous youth, as well as offer a means of intervention. The project will identify a set of mutually negotiated research aims alongside young Mapuche, developing a series of collaborative and participatory methods, including mapping, video and exhibition making, to offer a better understanding of indigenous experiences of the city as a kind of “in betweeness” - as expressed by the term Mapurbe, from mapu (earth) and urbe (city) - used to symbolize the on-going negotiation of marginality and displacement from the ancestral territory. The outcome of the collaborative research will be used to address the relationship with non-Mapuche citizens through two exhibitions (in Chile and Europe), offering young Mapuche an opportunity to make an active intervention into public discourse. The proposed research thus aims to apply theoretical knowledge, collaborative methods and modes of representation to issues of critical social interest in ways that are directly applicable to other context within Latin America and across Europe. The necessary training-through-research will be at the Instituto de Estudios Urbanos y Territoriales - Pontificia Universidad Católica (Chile), and at the Granada Centre for Visual Anthropology - University of Manchester (UK). This will provide the researcher with theoretical and technical competencies in Urban Studies and Visual Anthropology. The proposed research will contribute to the strengthening of European networking at an interdisciplinary and inter-continental level, building an international dialogue that will have positive and practical impacts on the European Research Area.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF MANCHESTER
Country: United Kingdom
Description: This project investigates the relationship between Chaucer's canonical status and his obscenity, both of which have been closely associated with the Canterbury Tales since Chaucer's death in 1400. Readers of the Canterbury Tales have made note of its occasionally indecorous language and content (particularly in relation to sex, the body, and bodily functions) ever since the earliest surviving manuscript was compiled c. 1405. But whereas obscenity is one of the major features of Chaucer's reputation in the eyes of present-day readers, many medieval and early modern readers viewed Chaucer’s obscene matter as standing at odds with his canonicity. This project traces the building tension between Chaucer's perceived obscenity and his literary reputation from his death in 1400 to the publication of poet laureate Robert Southey's expurgated version of the Canterbury Tales in 1831. By examining variations in the language and content of manuscripts, incunables, and print editions of the Canterbury Tales produced within this period (as well as reader annotations), I will show that scribes, readers, editors, and modernizers of Chaucer's most famous work persistently modify or comment on its language and content in an effort to downplay (or, occasionally, to enhance) what they perceive as obscene. I situate my findings alongside contemporaneous remarks by writers and editors regarding Chaucer's literary heritage in order to assess the relationship between variations in his reputation and variations in the Canterbury Tales. The project incorporates intensive training in the study of manuscripts and early printed books, and will result in at least 2 scholarly articles, a book proposal, and several conference presentations and public engagement initiatives intended to communicate my results to the widest possible audience. A MSCA Fellowship at the University of Oxford will enable me to work closely with a leading expert in the history of the book over the course of the project.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Country: United Kingdom
Description: Nonlinear dispersive partial differential equations (PDEs) appear ubiquitously as models describing wave phenomena in various branches of physics and engineering. Over the last few decades, multilinear harmonic analysis has played a crucial role in the development of the theoretical understanding of the subject. Furthermore, in recent years, a non-deterministic point of view has been incorporated into the study of nonlinear dispersive PDEs, enabling us to study typical behaviour of solutions in a probabilistic manner and go beyond the limit of deterministic analysis.
Loading Wayback Capture Info...
Loading video data...
Group: Projects completed before 1 January 2021
Coordinator: THE UNIVERSITY OF EDINBURGH
Country: United Kingdom
Page 1 of 3 (259 Total Results)Next Page ►
